Pharmacological effects:
The drug is a heart selective beta adrenergic receptor blockers, sympathetic to both endogenous activity and membrane stabilizing role. According to asthma medication in patients with bronchial spasm after the extent of (forced expiratory capacity) judgment, the heart of the goods were weaker than selective metoprolol and atenolol. Its role and propranolol electrophysiological similar period should not extend the atrioventricular node and atrioventricular slowed, but did not affect recovery time and sinus atrial or ventricular effective refractory period.

Pharmacokinetic :
The drug absorption after oral good oral absorption rate of 70%, oral after peak time is 2 to 4 h, bioavailability was 60%, plasma protein binding rate was only 15 percent, but combined with RBC stronger. The apparent volume of distribution of 1.0 to 3.0 L / kg. The plasma elimination half-life was 3 to 4 hours, effective plasma concentration of 0.2 to 2.0 μ g / ml. The drug acetylation of metabolites (diacetolol) more than the prototype drug pharmacological activity, its elimination semi-reduced> 12h. Mother and son-faecal excretion by the drug equal numbers, 15 percent to 60 percent by urinary excretion.

Adverse reactions:
Individuals can have heart failure.
The most common adverse reactions to fatigue, headache, gastrointestinal discomfort and dizziness. In bradycardia (<48 beats / min) is a rare.
The drug can cause allergic reactions have Arthus Ⅲ type, and is often the production of anti-nuclear antibodies.