We supply the Intermediates:
2,3,5-Collidine
2-Mercapto-5-Methoxy-1h-Benzimidazole
2-Chloromethyl-3,5-Dimethyl-4-Methoxy Pyridine Hcl
2 Hydroxymethyl 3,5 Dimethyl 4 Nitro Pyridine
2 Hydroxymethyl 3,5 Dimethyl 4 Methoxy Pyridine
2-(4-Methoxy-3,5-Dimethylpyridin-2-Yl-Methylthio)-5-Methoxy-1H-Imidazo(4,5-B)Pyridine
2-Mercapto-5-Methoxy-1H-Imidazo(4,5-B) Pyridine
4-Methoxy-2,3,5-Trimethylpyridine N-Oxide
CAS:73590-58-6
MF:C17H19N3O3S
MW:345.41616
Pharmacological effects:
In recent years the role of research and development mechanism different from the H2 receptor antagonist role of the new anti-peptic ulcer drug. Its specific role in gastric parietal cells, lower parietal cells in the hydrogen potassium ATPase activity, thereby inhibiting gastric acid and base induced gastric acid secretion. Because hydrogen potassium ATPase, also known as a "proton pump", so this type of drug is also known as the "proton pump inhibitor."
Indications:
Mainly applies to duodenal ulcer and Zhuo - Ai syndrome, can also be used for gastric ulcer and reflux esophagitis.
Role and purposes:
The Commodities role in the gastric parietal cells for H +-K +-ATPase inhibitor, selective secretion of gastric acid significantly inhibited the rapid onset of action, applicable to the stomach and duodenal ulcer, reflux esophagitis and gastric secretion in tumor.
